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Effects of Bio-active Desensitizer on Reduction of Tooth Sensitivity Caused by In-office Bleaching.

NCT06532526 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 51

Last updated 2024-08-01

No results posted yet for this study

Summary

The main aim of this randomized controlled clinical trial is to evaluate the efficacy of a bioactive glass desensitizer in reducing tooth sensitivity associated with in-office vital tooth bleaching. In addition, this study aims to compare the effectiveness of the bioactive glass desensitizer with that of a fluoride gel and a gel without desensitizing agent with regard to incidence, intensity, and duration of tooth sensitivity and, finally, to investigate how these agents affect tooth-shade following in-office bleaching. The hypothesis of the study is: There will be no difference in the effect of a bio-active glass desensitizer on tooth sensitivity associated with vital in-office tooth bleaching compared to a fluoride gel and the bio-active glass desensitizer has no effect on the bleaching efficacy.

Conditions

  • Tooth Discoloration

Interventions

OTHER

Predicta® Bioactive Desensitizer (PBD, PARKELL, EDGEWOOD, NY, USA)

A bioactive desensitizer gel that applied on teeth to reduce tooth sensitivity associated with dental bleaching.

OTHER

Gel with 1.23% sodium fluoride (EAZIGEL, VERICOM CO., LTD. SOUTH KOREA)

Fluoride gel that applied on the teeth to reduce tooth sensitivity

OTHER

Placebo gel without any active ingredients.

Water-based glycerin gel is used as the Placebo gel without active ingredients

Sponsors & Collaborators

  • King Abdullah University Hospital

    lead OTHER

Principal Investigators

  • Ghada A Maghaireh · Jordan University of Science and Technology

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-07-01
Primary Completion
2025-01-30
Completion
2025-04-01

Countries

  • Jordan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06532526 on ClinicalTrials.gov