MedTrace Logo

Efficacy and Safety of a Topical Botanical Extract Formulation for Skin Barrier Repair

NCT07645339 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 35

Last updated 2026-06-16

No results posted yet for this study

Summary

This is a single-center, double-blinded, placebo-controlled, prospective clinical study designed to evaluate the skin barrier repair efficacy and local tolerance of topical cosmetic formulations containing a botanical extract. Skin barrier challenge is induced via standardized tape stripping on the volar forearm of healthy subjects. The study will evaluate and compare the repair kinetics of two concentrations of the active formulation, a vehicle, and an untreated control zone over a 14-day application period.

Conditions

  • Impaired Barrier

Interventions

OTHER

Cosmetic Topical Product B

Topical skincare formulation containing Botanical Extract (Concentration B). Applied twice daily for 14 days.

OTHER

Vehicle

Topical formulation base (identical to investigational products but without the active botanical extract). Applied twice daily for 14 days.

OTHER

Cosmetic Topical Product A

Topical skincare formulation containing Botanical Extract (Concentration A). Applied twice daily for 14 days.

Sponsors & Collaborators

  • L'Oreal

    lead INDUSTRY

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
35 Years
Max Age
60 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-10-13
Primary Completion
2025-11-03
Completion
2026-07-25

Countries

  • China

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07645339 on ClinicalTrials.gov