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Impact of Trans-catheter Aortic Valve Implantation on Renal Function

NCT07626710 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000

Last updated 2026-06-04

No results posted yet for this study

Summary

Both contrast-induced acute kidney injury (AKI) and pre-existing chronic kidney disease are associated with an increased mortality risk in patients requiring aortic valve replacement. Nonetheless, the direct haemodynamic impact of the aortic barrage (i.e. pre-renal mechanism) on renal function compromising and its reversibility in patients undergoing trans-catheter aortic valve implantation (TAVI) is unknown.

This registry aims to evaluate the effect of severe aortic stenosis removal on the risk of contrast-induced acute renal injury (CI-AKI) during TAVI procedures and on renal function evolution

Conditions

  • Aortic Valve Stenosis
  • Chronic Kidney Diseases
  • Renal Failure Acute Chronic

Interventions

PROCEDURE

Trans-catheter aortic valve implantation (TAVI)

Transcatheter aortic valve implantation (TAVI) for severe aortic stenosis

Sponsors & Collaborators

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    lead OTHER

Principal Investigators

  • Enrico Romagnoli · Fondazione Policlinico Universitario Agostino Gemelli

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-08-30
Primary Completion
2028-08-30
Completion
2033-08-30

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07626710 on ClinicalTrials.gov