MedTrace Logo

Remote Ischemic Preconditioning for Renal Protection in TAVI

NCT03347032 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 46

Last updated 2022-12-14

No results posted yet for this study

Summary

Severe aortic stenosis remains a major cause of morbidity and mortality of the elderly affecting approximately 3% of elderly patients with an increasing number of patients undergoing transcatheter aortic valve interventions. As part of pre-procedural planning these patients undergo CT scans and receive contrast during the procedure. These patients often have baseline renal insufficiency and are high risk of contrast induced nephropathy despite pre-hydration techniques. The purpose of this study is to evaluate the efficacy of this simple and safe procedure in preventing renal injury in this particular population.

Conditions

  • Aortic Valve Stenosis
  • Renal Insufficiency
  • Contrast-induced Nephropathy

Interventions

PROCEDURE

Remote ischemic preconditioning

Serial inflations and deflations as detailed in the arm/group descriptions

PROCEDURE

Control

Serial inflations and deflations as detailed in the arm/group descriptions

Sponsors & Collaborators

  • Henry Ford Health System

    lead OTHER

Principal Investigators

  • William O'Neill, MD · Henry Ford Health System

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-02-13
Primary Completion
2018-12-30
Completion
2018-12-30

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03347032 on ClinicalTrials.gov