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Neural Mechanisms of Emotion-behaviour Interactions

NCT07623746 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2026-06-03

No results posted yet for this study

Summary

Deciding what to do when for how long - self-organizing one's behaviour - is an important feature of daily life. Emotions arise providing short-cuts for the computational complexities. Yet, one still knows relatively little about the underlying cognitive and neural mechanisms. EMOBB will establish the computational, cognitive and neural underpinnings of the rich interplay between emotions and self-organized behaviour in naturalistic environments. Previous work has almost exclusively relied on tasks structured into experimenter determined trials - thus how people self-organized behaviour could not be measured. To overcome this, EMOBB will combine novel naturalistic tasks in which people have freedom what to do when for how long with subjective and objective measurements of emotions. This will be made possible through a computational modelling approach that allows dissecting and quantifying even complex behaviour-emotion interactions.

Specifically, EMOBB will use three cognitive tasks of emotion-behaviour interplay that participants will do while undergoing functional magnetic resonance brain imaging and monitoring of their facial expressions with an MRI-compatible camera.

The primary hypothesis of EMOBB is that both unique and shared neural networks will underpin the interplay between emotions and behaviour across our cognitive tasks.

Conditions

  • Healthy Volunteer

Interventions

OTHER

Functional Magnetic Resonance Imaging (fMRI)

Participants will perform a cognitive task (responses through button presses) while we measure brain activity with functional magnetic resonance imaging (fMRI) and record their facial expressions.

Sponsors & Collaborators

  • Hospices Civils de Lyon

    lead OTHER

Principal Investigators

  • Jacqueline SCHOLL, PhD · Institut National de la Santé Et de la Recherche Médicale, France

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-10-01
Primary Completion
2030-10-01
Completion
2030-10-10

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07623746 on ClinicalTrials.gov