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Right Ventricular Function and Respiratory Acidosis After Cardiac Surgery

NCT07619274 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 220

Last updated 2026-06-01

No results posted yet for this study

Summary

Right heart dysfunction remains a frequent cause of morbidity and mortality after cardiac surgery. Respiratory acidosis, particularly when accompanied by hypoxemia, plays a significant role in right heart failure, primarily by increasing right ventricular afterload through pulmonary vasoconstriction and elevated pulmonary arterial pressures. This phenomenon leads to increased right ventricular workload, causing dilation, decreased contractility, and ultimately right heart failure. The study aims to evaluate the effect of respiratory acidosis on right ventricular function after cardiac surgery.

Conditions

  • Respiratory Acidosis in ICU Patients
  • Right Ventricular (RV) Dysfunction
  • Hemodynamic Changes
  • Mechanical Ventilation

Interventions

OTHER

Not applicable- observational study

No intervention

Sponsors & Collaborators

  • Laval University

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-05-31
Primary Completion
2026-08-31
Completion
2026-10-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07619274 on ClinicalTrials.gov