Expanding Genetic Access for Prostate Cancer Survivors

Summary

The goal of this study is to increase genetic education and genetic testing for hereditary cancer risk among prostate cancer survivors. The study will:

Test the effectiveness of a digital guide (DG+) vs. print guide (Print+) vs. enhanced usual care (EUC) on engagement in genetic education and uptake of genetic testing.

Evaluate the impact of the DG+ vs. Print+ vs. EUC on the process that participants use to make decisions and evaluate effects on well-being (also called psychosocial outcomes).

Explore the ways (methods) that influence how participants experience the intervention.

The main questions this study aims to answer are: which group - the digital guide (DG+) group, print (Print+) group or the EUC group - is more likely to request genetic testing and which group is more likely to get (engage with) genetic education.

Participants will be randomly assigned to either the digital guide (DG+) group, the print guide (Print+) group or EUC group. Each group will receive genetic education and have an opportunity to request genetic testing. Researchers will compare the three groups to determine which is most most likely to complete genetic testing (GT) and which group engages more with genetic education.

Conditions

• Prostate Cancer Patients
• Hereditary Cancer
• Genetic Testing

Interventions

BEHAVIORAL

Print Genetic Education Guide

Consists of clinical letter, genetic testing kit, and a print genetic education guide along with streamlined access to genetic testing for hereditary cancer risk.

BEHAVIORAL

Digital Guide Genetic Education Guide

Consists of clinical letter, genetic testing kit, and access to a genetic education digital guide along with streamlined access to genetic testing for hereditary cancer risk.

BEHAVIORAL

Enhanced Usual Care

Consists of clinical letter and recommendation/referral to schedule a genetic counseling session.

Sponsors & Collaborators

• National Cancer Institute (NCI)

  collaborator NIH

• Rutgers University

  collaborator OTHER

• Georgetown University

  lead OTHER

Study Design

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

80 Years

Sex

MALE

Healthy Volunteers

No

Timeline & Regulatory

Start

2026-08-01

Primary Completion

2029-07-30

Completion

2030-07-31

Countries

• United States

Study Locations