Technology-Enhanced Acceleration of Germline Evaluation for Therapy, TARGET Study

Summary

This trial performs user testing of a mobile-friendly patient history collection and genetic education tool to improve healthcare providers' understanding of prostate cancer genetic testing. This trial also compares traditional genetic counseling versus a web-based genetic education (WBGE) tool to provide information about genetic testing to men with prostate cancer. The WBGE tool has educational modules on genetic counseling and testing, as well as a patient history collection tool to help providers learn which patients may carry genetic mutations and may be considered for genetic counseling and genetic testing. The purpose of this research is to use technology to deliver information on genetic testing for prostate cancer to patients to help them decide whether or not to receive genetic testing.

Conditions

• Biochemically Recurrent Prostate Carcinoma
• Metastatic Prostate Carcinoma
• Stage IIIB Prostate Cancer AJCC v8
• Stage IIIC Prostate Cancer AJCC v8
• Stage IV Prostate Cancer AJCC v8

Interventions

OTHER

Genetic Counseling

Receive in-person, telehealth, or over-the-phone genetic counseling

OTHER

Internet-Based Intervention

Use web-based genetic education tool online

GENETIC

Genetic Testing

Undergo genetic testing

OTHER

Survey Administration

Ancillary Studies

OTHER

Genetic Counseling

Receive in-person, telehealth, or over-the-phone genetic counseling

GENETIC

Genetic Testing

Undergo genetic testing

OTHER

Survey Administration

Ancillary Studies

OTHER

Interview

Attend Interview

OTHER

Internet Based Intervention

Use web-based genetic education tool online

OTHER

Survey Administration

Ancillary Studies

Sponsors & Collaborators

• Prostate Cancer Foundation

  collaborator OTHER

• Thomas Jefferson University

  lead OTHER

Principal Investigators

• Veda Giri, MD · Clinical Cancer Genetics Yale School of Medicine

• Stacy Loeb, MD, MSc · NYU- Langone Health, Manhattan VA Hospital

Study Design

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2020-08-27

Primary Completion

2022-08-09

Completion

2024-09-10

Countries

• United States

Study Locations