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AGEWISE: Unravelling the Gut-Hormone Axis in Women's Ageing

NCT07614542 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2026-05-29

No results posted yet for this study

Summary

AGEWISE is an observational study that aims to understand how changes in gut microbiome are related to hormonal changes during women's ageing, particularly across the different stages of menopause. The study will include healthy women aged 40 to 64 years living in Portugal, who will provide stool and blood samples and complete questionnaires about their health, lifestyle, diet, and menopausal symptoms. Researchers will study the gut microbiome together with hormone levels and markers of inflammation to better understand how menopause affects long-term health and to support the development of improved prevention strategies for women.

Conditions

  • Menopause
  • Gut Microbiome
  • Hormonal Changes
  • Chronic Low-Grade Inflammation
  • Inflammaging

Sponsors & Collaborators

  • Biocodex Microbiota Foundation

    collaborator UNKNOWN

  • Gulbenkian Institute for Molecular Medicine

    lead OTHER

Eligibility

Min Age
40 Years
Max Age
64 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-06-02
Primary Completion
2026-12-31
Completion
2036-12-31

Countries

  • Portugal

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07614542 on ClinicalTrials.gov