Clinical Study of BMP-2 Injectable Hydrogel for Promoting Alveolar Bone Regeneration
NCT07611617 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80
Last updated 2026-05-28
Summary
This project aims to construct an injectable self-healing hydrogel loaded with BMP-2, with optimized gelation time and mechanical strength to meet the requirements for periodontal pocket filling, for the treatment of periodontitis and acceleration of tissue repair, achieving a "bactericidal-anti-inflammatory-regenerative" trinity function. This project will provide a novel intelligent material for promoting alveolar bone regeneration in periodontitis and establish a theoretical paradigm for the precise intervention of oral infectious diseases.
Conditions
- Periodontitis
- Alveolar Bone Loss* / Therapy
Interventions
- OTHER
-
treatment group
subgingival scaling + BMP-2 hydrogel
Sponsors & Collaborators
-
The First Affiliated Hospital of Xinxiang Medical College
lead OTHER
Principal Investigators
-
Wenjie Ren · The First Affiliated Hospital of Xinxiang Medical College
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-05-01
- Primary Completion
- 2027-12-31
- Completion
- 2028-12-31
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