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Long-Term Risk of Kidney Stones in Living Kidney Donors

NCT07611500 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 50000

Last updated 2026-05-28

No results posted yet for this study

Summary

Using a population-based, matched, retrospective cohort approach, this study will evaluate the long-term risk of kidney stones among living kidney donors compared with matched healthy nondonors. Linked administrative health care databases from Ontario, Alberta, and British Columbia will be used and living kidney donors who donated between 1992 and 2024 will be identified and matched 1:10 to a carefully selected population of healthy nondonors based on baseline characteristics. The primary outcome is a surgical intervention for kidney stones (including shockwave lithotripsy, ureteroscopy or percutaneous nephrolithotomy). The secondary outcome is a hospital encounter with a kidney stone diagnosis.

Conditions

  • Kidney Stones, Urolithiasis, Hypocitraturia
  • Living Kidney Donation
  • Living Kidney Donor

Interventions

PROCEDURE

Living kidney donation

Nephrectomy for living kidney donation

Sponsors & Collaborators

  • London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
105 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
1992-07-01
Primary Completion
2024-03-31
Completion
2025-03-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07611500 on ClinicalTrials.gov