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Socket Preservation Using Autogenous Dentin

NCT07608289 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2026-05-27

No results posted yet for this study

Summary

Tooth extraction leads to a substantial reduction in alveolar bone volume, with up to 25% loss within the first year and up to 40-60% within three years. This prospective randomized clinical study aims to compare four commonly used methods of alveolar ridge preservation, evaluating their effectiveness in maintaining bone volume for later prosthetic or implant rehabilitation. Alveolar dimensions will be measured using calibrated CBCT imaging pre-extraction and at six months post-extraction.

Conditions

  • Tooth Extraction Site Healing

Interventions

PROCEDURE

Tooth extraction left to heal spontaneously

Wound after the tooth extraction will be secured with a stitch without addition of any augmentation material.

PROCEDURE

Tooth extraction plus collagen sponge

Wound after the tooth extraction will be filled with a collagen sponge (Parasorb Cone, Resorba, Germany) and secured with a stitch.

PROCEDURE

Tooth extraction plus tricalcium phosphate

Wound after the tooth extraction will be filled with tricalcium phosphate xenograft (Poresorb TCP, Lasak, Czech Republic), covered with a collagen sponge (Parasorb Cone, Resorba, Germany), and secured with a stitch.

PROCEDURE

Tooth extraction plus autogenous dentin

Wound after the tooth extraction will be filled with grounded autogenous dentin, covered with a collagen sponge (Parasorb Cone, Resorba, Germany), and secured with a stitch.

Sponsors & Collaborators

  • University Hospital Ostrava

    collaborator OTHER

  • Private dental practice Jalůvka

    collaborator UNKNOWN

  • University of Ostrava

    lead OTHER

Principal Investigators

  • Martin Starosta, Assoc. Prof. · University of Ostrava

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-01-01
Primary Completion
2027-12-31
Completion
2028-12-31

Countries

  • Czechia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07608289 on ClinicalTrials.gov