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The Effect of Intraoperative Esketamine Infusion on Pruritus in Elderly Surgical Patients

NCT07597486 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 200

Last updated 2026-05-19

No results posted yet for this study

Summary

To explore the effect of intraoperative esketamine on pruritus in elderly patients undergoing elective general anesthesia for knee replacement surgery

Conditions

  • Senile Pruritus

Interventions

DRUG

Normal Saline

An equal volume of normal saline is intravenously administered 30 minutes prior to the completion of the operation.

DRUG

Esketamine

Esketamine 0.2 mg/kg is intravenously administered 30 minutes prior to the completion of the operation.

Sponsors & Collaborators

  • Tianjin Medical University General Hospital

    lead OTHER

Principal Investigators

  • Guolin Wang · Tianjin Medical University General Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
65 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-05-15
Primary Completion
2027-06-20
Completion
2027-09-30

Countries

  • China

Study Locations

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Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07597486 on ClinicalTrials.gov