MIRNA QUANTIFICATION IN PATIENTS WITH SEPTIC SHOCK
NCT07597122 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 56
Last updated 2026-05-22
Summary
Sepsis-induced immunosuppression (SIS) is a common complication in patients with septic shock. Reduced expression of Human leukocyte antigen isotype DR (HLA-DR) on circulating monocytes is a marker for SIS and correlates with risk of secondary infections and mortality. The miRSep study aims to improve the understanding of early microRNA (miRNA) mediated changes in HLA-DR on monocytes in patients with septic shock.
Conditions
- Sepsis and Septic Shock
Sponsors & Collaborators
-
Insel Gruppe AG, University Hospital Bern
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-06-01
- Primary Completion
- 2027-05-31
- Completion
- 2027-12-31
Countries
- Switzerland
Study Locations
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