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Hep Mec Cohort in Zambia

NCT07589985 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 390

Last updated 2026-05-15

No results posted yet for this study

Summary

Observational cohort of adults with acute and chronic hepatitis B infection in Zambia, with and without HIV coinfection. Participants join the study at the time of diagnosis and before or at the time when they are starting antiviral treatments and then they are followed up over multiple years to assess changes to their liver and evolution of HBV (and HIV if applicable) infection. All treatments for HBV and HIV are standard per local Ministry of Health guidelines.

Conditions

Sponsors & Collaborators

  • National Institute of Allergy and Infectious Diseases (NIAID)

    collaborator NIH

  • Centre for Infectious Disease Research in Zambia

    collaborator OTHER

  • Tropical Gastroenterology and Nutrition Group

    collaborator UNKNOWN

  • University of Zambia

    collaborator OTHER

  • Massachusetts General Hospital

    collaborator OTHER

  • Weill Medical College of Cornell University

    collaborator OTHER

  • University of Alabama at Birmingham

    lead OTHER

Principal Investigators

  • Michael Vinikoor, MD · University of Alabama at Birmingham

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-09-28
Primary Completion
2029-08-31
Completion
2030-08-31

Countries

  • Zambia

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07589985 on ClinicalTrials.gov