Hepatitis B is a viral liver infection caused by the hepatitis B virus that can present as acute or chronic disease. Chronic infection can lead to cirrhosis, liver failure, and hepatocellular carcinoma. Transmission occurs through blood and body fluids, including perinatal, sexual, and parenteral routes.
Trump secured agreements with 16 pharmaceutical companies tied to TrumpRx.gov, including most-favoured-nation pricing and direct-to-patient discounts. Several companies disclosed price cuts for obesity, diabetes, insulin and other medicines.
A federal judge froze appointments to the CDC’s ACIP, halted its votes, and paused recent HHS vaccine policy changes. The ruling leaves several FDA-approved vaccines pending review.
Scientists are testing experimental cancer therapies including mRNA therapeutic vaccines, engineered EcN bacteria that deliver romidepsin in mice, and macrophage-targeted CAR T cells.
The American Medical Association and University of Minnesota's Vaccine Integrity Project are creating an independent vaccine review system after major changes at the CDC raised concerns among public health experts.
The CDC's vaccine advisory committee meeting scheduled for February 25-27 has been canceled and rescheduled for March 18-19, as medical groups challenge the panel's composition and policies under Health Secretary Robert F. Kennedy Jr.
Ralph Abraham resigned as CDC principal deputy director after less than two months, leaving the agency's top two positions vacant. The departure is part of broader HHS leadership changes under Secretary Robert F. Kennedy Jr.
Vir Biotechnology is set to report Q4 2025 earnings on Feb 23, 2026, with analysts expecting revenue of $19.91-$23.18 million and a loss of $0.41-$0.50 per share, marking a 61% year-over-year revenue increase.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07589985 |
Hep Mec Cohort in Zambia |
RECRUITING | |
| NCT07253220 |
TAF Monotherapy Versus ETV Combined With TAF on the Efficacy and Prognosis of Immunotherapy for Hepatitis B-Related Hepatocellular Carcinoma |
NOT_YET_RECRUITING | NA |
| NCT07168356 |
A Study to Evaluate Blood Levels of Bepirovirsen in Adult Participants With Severe or Moderate Kidney Disease |
ACTIVE_NOT_RECRUITING | PHASE1 |
| NCT07154212 |
Hepatitis B Virus Reactivation in COVID-19 |
COMPLETED | |
| NCT07126041 |
Scalable Public Health Empowerment, Research, and Education Sites (SPHERES) |
NOT_YET_RECRUITING | NA |
| NCT07085715 |
Pan-Viral Screening and Linkage to Care Among GBMSM and Trans Women in Spain |
NOT_YET_RECRUITING | |
| NCT07079150 |
Real-world Study Evaluating the Long-term Outcomes of Pegylated Interferon α-2b Treatment in the Families With Clusters of HBV Infection and Unfavorable Prognosis - A Prospective, Controlled, Multicenter, Cohort Study |
RECRUITING | |
| NCT06998992 |
Assessing the Reliability of Self-Reported Hepatitis B Vaccination Status in Outpatients: Evaluation of Individuals Born in France and Consulting at the CeGIDD in Saint-Denis. |
COMPLETED | |
| NCT06947499 |
A Phase II/III Study to Evaluate the Immunogenicity, Safety and Lot-to-lot Consistency of LBVD, a Fully Liquid Hexavalent Diphtheria-tetanus-whole Cell Pertussis-hepatitis B-poliovirus-Haemophilus Influenzae Type b Conjugate (DTwP-HepB-IPV-Hib) Vaccine, in Healthy Infants as Primary Series |
RECRUITING | PHASE2/PHASE3 |
| NCT06947356 |
Comparison of TAF and TDF in Preventing Mother-to-Child Transmission of HBV in Pregnancies With High Viral Loads |
RECRUITING | NA |
