HBV Vaccination: Birth Dose Safe, May Reduce HIV Coinfection
Systematic review confirms hepatitis B birth dose is safe and effective; separate study finds childhood vaccination linked to significantly lower HBV coinfection in people with HIV.
Hepatitis B
DiseaseAlso known as: HBV
Disease Profile
Hepatitis B is a viral liver infection caused by the hepatitis B virus that can present as acute or chronic disease. Chronic infection can lead to cirrhosis, liver failure, and hepatocellular carcinoma. Transmission occurs through blood and body fluids, including perinatal, sexual, and parenteral routes.
- Category
- Viral infectious liver disease
- Prevalence
- WHO estimated 254 million people were living with chronic hepatitis B infection in 2022
- B18.1
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| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07637214 |
A Real-world Study: Analysis of the Efficacy of Antiviral Therapy in CHB Patients Over 30 Years Old, HBV DNA Positive and ALT Normal |
COMPLETED | |
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Hep Mec Cohort in Zambia |
RECRUITING | |
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NOT_YET_RECRUITING | NA |
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COMPLETED | |
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COMPLETED | |
| NCT06947499 |
A Phase II/III Study to Evaluate the Immunogenicity, Safety and Lot-to-lot Consistency of LBVD, a Fully Liquid Hexavalent Diphtheria-tetanus-whole Cell Pertussis-hepatitis B-poliovirus-Haemophilus Influenzae Type b Conjugate (DTwP-HepB-IPV-Hib) Vaccine, in Healthy Infants as Primary Series |
RECRUITING | PHASE2/PHASE3 |