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Gut Microbiome Response to Long-Haul Travel in Elite Football Players

NCT07585474 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2026-05-13

No results posted yet for this study

Summary

The goal of this randomised control trial is to measure the gut microbiome response to long-haul travel alongside the demands of pre-season amongst elite football players. The efficacy of a probiotic in modulating the gut microbiome to mitigate the detrimental impacts of long-haul travel as well as training in the heat will also be explored.

The main questions this study aims to answer are:

* How is the gut microbiome of the professional football player impacted by long-haul travel during the pre-season period?
* How is immune function impacted by the demands of pre-season?
* Can a probiotic dietary maintain gut microbial stability in response to long-haul travel? Researchers will compare the effects of the probiotic supplement with a placebo.

Participants will be required to:

* Provide a faecal sample at multiple points throughout the pre-season
* Provide a saliva sample at multiple points throughout the season
* Consume a daily supplement which will either be a placebo or probiotic capsule

Conditions

  • Microbial Composition
  • Immune Function

Interventions

DRUG

Probiotic Capsule

Probiotic capsule administered orally once daily for 3 weeks

DRUG

Placebo

Placebo tablet, identical in appearance to probiotic, administered orally once daily for 3-4 weeks.

Sponsors & Collaborators

  • University of Leeds

    collaborator OTHER

  • Sheffield Hallam University

    lead OTHER

Principal Investigators

  • George Davis, Masters · Sheffield Hallam University

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-07-25
Primary Completion
2025-08-18
Completion
2026-08-15

Countries

  • United States
  • United Kingdom

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07585474 on ClinicalTrials.gov