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PRP Improves Blastocyst Formation in ICSI Cycles

NCT07579858 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 66

Last updated 2026-05-12

No results posted yet for this study

Summary

The goal of this clinical trial is to learn if platelet rich plasma (PRP) works to improve embryo development rates and embryo quality in IVF cycles, involving male adult patients with severe sperm disorders.

The main questions it aims to answer are:

* Does PRP improve sperm quality of male adult patients undergoing IVF?
* Does PRP improve embryo development and embryo quality of the IVF patients?

Researchers will compare embryos from IVF patients treated with PRP to those not treated with PRP to see if PRP improves embryo development and embryo quality.

Participants will:

* Provide semen sample for IVF
* Provide blood sample for PRP preparation
* Have PRP obtained from their blood added to their sperm sample

Conditions

  • Severe Oligoasthenoteratozoospermia
  • Sperm Quality
  • Spermatazoa Disorders
  • Sperm Parameters in Fertile and Infertile Men
  • Embryo Development
  • Embryo Quality
  • Embryologic Parameters
  • Platelet Rich Plasma
  • Platelet Rich Plasma (PRP)
  • Blastocyst Quality
  • Blastocyst IVF
  • Blastocyst
  • Blastocysts

Interventions

BIOLOGICAL

Platelet Rich Plasma

Platelet-rich plasma (PRP) will be prepared from autologous blood collected from each participant. The blood sample will undergo centrifugation at 1400 rpm for 15 minutes to separate and concentrate the platelet-rich fraction. The resulting PRP will then be isolated and added to the participant's sperm sample for use in the IVF procedure.

Sponsors & Collaborators

  • Halim Fertility Center

    collaborator INDUSTRY

  • Stella Maris Women and Children Hospital

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
28 Years
Max Age
45 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-01-01
Primary Completion
2023-08-30
Completion
2023-12-30

Countries

  • Indonesia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07579858 on ClinicalTrials.gov