A Prospective Observational Cohort Study Protocol for Disease Severity Stratification and Prognosis Assessment in Patients With Pneumonia
NCT07567911 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 2700
Last updated 2026-05-05
Summary
This is a prospective, multicenter observational cohort study involving approximately 2,700 patients, designed to delineate the natural history of pneumonia by tracking the complete clinical course and dynamic multi-omics evolution from the acute phase to recovery; the study aims to quantify severe conversion rates and mortality by comparing baseline characteristics, pathogen distribution, and immune response trajectories between severe and non-severe groups, ultimately revealing the underlying molecular mechanisms of disease progression and optimizing clinical risk stratification strategies.
Conditions
- Severe Pneumonia
- Pneumonia
Sponsors & Collaborators
-
Fifth Affiliated Hospital of Guangzhou Medical University
collaborator OTHER -
Zhonghao Fang
lead OTHER
Principal Investigators
-
Zifeng Yang, Doctor · The First Affiliated Hospital of Guangzhou Medical University
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-05-01
- Primary Completion
- 2026-05-01
- Completion
- 2028-05-28
Countries
- China
Study Locations
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