Study on the Etiology, Risk Factors and Pathogenesis of COPD Based on Clinical Bioinformatics

Summary

The risk factors and causes of chronic obstructive pulmonary disease（COPD）are not clear, so the prevalence of COPD is high and the prevention effect is not good. Because the pathogenesis of COPD is not completely elucidated, the diagnosis and classification of COPD are inaccurate which resulting in poor efficacy of treatment. Therefore, it is of great scientific and clinical significance to find out the risk factors and causes of COPD, to clarify its pathogenesis, to put forward the prevention and early intervention measures of COPD, to warn the occurrence of COPD, to predict the deterioration of the disease, to reduce the occurrence of COPD and to slow down the progress of COPD.

The project establishes a cohort of COPD people，high-risk group and the healthy group. The project studys the risk factors, etiology and pathogenesis of COPD. The project studys the interaction between genetic factors and environmental factors on COPD and its effect on pathogenesis, progression and outcome of COPD.

Conditions

• Chronic Obstructive Pulmonary Disease

Sponsors & Collaborators

• Shanghai Zhongshan Hospital

  collaborator OTHER

• The Second Affiliated Hospital of Fujian Medical University

  collaborator OTHER

• The First Affiliated Hospital of Zhengzhou University

  collaborator OTHER

• Xibei Hospital

  collaborator OTHER

• Henan Provincial People's Hospital

  collaborator OTHER

• Shenzhen University

  collaborator OTHER

• Shantou University Medical College

  collaborator OTHER

• Shanghai Minhang Central Hospital

  collaborator OTHER

• Shanghai Fengxian District Central Hospital

  collaborator OTHER

• Sun Med IT(ShangHai) Co. Ltd

  collaborator UNKNOWN

• First Affiliated Hospital of Wenzhou Medical University

  lead OTHER

Principal Investigators

• ChengShui Chen · First Affiliated Hospital of Wenzhou Medical University

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2017-12-10

Primary Completion

2022-12-31

Completion

2022-12-31

Countries

• China

Study Locations