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Clinical Features and Outcomes of VZV CNS Infections

NCT07554261 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2026-04-28

No results posted yet for this study

Summary

The goal of this observational study is to learn about the clinical characteristics, risk factors, and long-term outcomes of varicella zoster virus (VZV)-related central nervous system (CNS) infections in adults. The main questions it aims to answer are:

What are the risk factors associated with VZV meningitis and encephalitis? Which clinical and laboratory findings are associated with complications and poor functional outcomes? Researchers will collect retrospective data from participating centers across the country, including demographic, clinical, laboratory, imaging, and treatment variables. Participants diagnosed with VZV-related central nervous system infections will be followed through medical records, and outcomes such as complications, functional status, and mortality will be evaluated.

Conditions

  • Varicella Zoster
  • Varicella Meningitis
  • Varicella Encephalitis
  • Varicella Neurological

Sponsors & Collaborators

  • Kocaeli University

    lead OTHER

Principal Investigators

  • Özlem Güler, MD · Kocaeli University, Kocaeli, Turkey

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-04-17
Primary Completion
2026-06-01
Completion
2026-07-07

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07554261 on ClinicalTrials.gov