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Efficacy of Oral Famciclovir Versus Aciclovir Treatment in Patients With Herpes Zoster

NCT01327144 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 177

Last updated 2019-04-17

No results posted yet for this study

Summary

Herpes Zoster is an infection that affects part of the nervous system caused by Varicella Zoster Virus. Herpes Zoster manifests as vesicular eruption in the dermatome, often associated with significant pain.

There are effective oral prescription antiviral medicines available to reduce the discomfort of symptoms as famciclovir and aciclovir.

This is a phase III, multicenter, randomized, parallel-group study to compare the efficacy and safety of treatment with Famciclovir (500 mg) comparing to Aciclovir (400 mg) in patients with Herpes Zoster.

Conditions

  • Herpes Zoster

Interventions

DRUG

Famciclovir

Famciclovir 500 mg- 1 tablet each 12 hours for 7 days

DRUG

Aciclovir

Aciclovir 400 mg- 02 tablets each 4 hours for 7 days

Sponsors & Collaborators

  • EMS

    lead INDUSTRY

Principal Investigators

  • Joyce Silva, MD · EMS

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-06-30
Primary Completion
2017-05-31
Completion
2017-07-31

Countries

  • Brazil

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01327144 on ClinicalTrials.gov