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Acupuncture and Exercise for EV-Pembro-Induced Peripheral Neuropathy

NCT07548476 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2026-05-04

No results posted yet for this study

Summary

The goal of this study is to evaluate the feasibility and preliminary efficacy of a combined acupuncture and exercise intervention for the management of chemotherapy-induced peripheral neuropathy (CIPN) in participants with metastatic bladder cancer receiving enfortumab vedotin (EV) and pembrolizumab (Pembro).

The names of the two study groups in this research study are:

* Acupuncture + Virtual Exercise (AVE)
* Virtual Exercise Only (VE)

Conditions

  • Metastatic Bladder Cancer
  • Peripheral Neuropathy
  • Advanced Urothelial Cancer
  • Metastatic Urothelial Cancer

Interventions

PROCEDURE

Acupuncture

Acupuncture treatment with licensed acupuncturist.

BEHAVIORAL

Exercise

Virtually supervised, technology-based aerobic and resistance exercise program. Exercise bike and resistance bands will be provided to participants. Exercise sessions will be via HIPAA-compliant, teleconference platform Zoom.

Sponsors & Collaborators

Principal Investigators

  • Christina Dieli-Conwright, PhD, MPH · Dana-Farber Cancer Institute

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-10-02
Primary Completion
2027-03-02
Completion
2027-03-02

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07548476 on ClinicalTrials.gov