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Exercise Effect on Chemotherapy-Induced Neuropathic Pain

NCT02991677 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2024-08-06

No results posted yet for this study

Summary

Chemotherapy-induced peripheral neuropathy (CIPN) continues to be a serious healthcare concern. It is painful, persistent, resistant to conventional pain therapies, and results in long-term suffering and decreased quality of life for many cancer survivors. The role of exercise to decrease CIPN-related neuropathic pain (CIPN-NP) will be investigated, with the goal of identifying the mechanisms associated with this therapeutic approach to manage CIPN-NP.

Conditions

  • Cancer, Breast
  • Cancer, Colorectal
  • Cancer, Lung
  • Cancer, Ovarian

Interventions

BEHAVIORAL

aerobic exercise intervention

Exercise physiologist supervised walking or running on the treadmill 3 times weekly for 12 weeks.

OTHER

control group

weekly contact by study staff with survivorship information offered not related to neuropathy.

BEHAVIORAL

resistive training

Exercise physiologist supervised upper and lower extremity resistive training 3 times weekly for 12 weeks

Sponsors & Collaborators

  • Baltimore VA Medical Center

    lead FED

Principal Investigators

  • Alice Ryan, PhD · University of Maryland at Baltimore School of Medicine

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-03-01
Primary Completion
2025-06-30
Completion
2025-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02991677 on ClinicalTrials.gov