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Effect of Rosmarinus Officinalis Extract on Oxidative Stress and Inflammatory Biomarkers in Patients With Type 2 Diabetes (T2DM)

NCT07541729 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2026-08-26

No results posted yet for this study

Summary

This randomized, placebo-controlled clinical trial evaluates the effects of a methanolic extract of Rosmarinus officinalis (rosemary) in patients with type 2 diabetes mellitus. Participants are randomly assigned to receive either methanolic rosemary extract or placebo in addition to their usual treatment and are followed for six months. A data cut-off at Month 3 is used for the analysis of metabolic, oxidative stress, and cytogenetic outcomes, while selected inflammatory and cardiovascular biomarkers continue to be assessed through Month 6. The study investigates the potential complementary effects of methanolic rosemary extract on metabolic control, oxidative stress, inflammation, genomic stability, and cardiovascular-related biomarkers in patients with type 2 diabetes mellitus.

Conditions

  • Type 2 Diabetes Mellitus (T2DM)
  • Oxidative Stress
  • Inflammation Chronic

Interventions

OTHER

Placebo

Inactive substance with no therapeutic effect.

DIETARY_SUPPLEMENT

Rosmarinus officinalis extract

Methanolic extract of Rosmarinus officinalis administered orally for 12 weeks

Sponsors & Collaborators

  • Universidad Autonoma de Zacatecas

    lead OTHER

Principal Investigators

  • Diana J Soriano Gálvez, M. en C. · Sin afiliación

  • Sandy F Rodriguez Reyes, Dr. · Sin afiliación

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-09-20
Primary Completion
2026-06-01
Completion
2027-01-31

Countries

  • Mexico

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07541729 on ClinicalTrials.gov