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Low-Flow Anesthesia Without Wash-in: Effects on Oxygenation and Depth of Anesthesia

NCT07534839 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2026-04-16

No results posted yet for this study

Summary

This study aims to evaluate whether adjusting the fresh gas flow rate to low-flow immediately after intubation, without performing a wash-in, is a reliable approach with respect to depth of anesthesia and oxygenation.

Conditions

  • Low Flow Anesthesia

Interventions

DEVICE

Initiation of low-flow anesthesia without wash-in following intubation

After endotracheal intubation, fresh gas flow is set to 0.75 L/min with 60% O₂. The sevoflurane vaporizer is initially set to 8%, and the sevoflurane concentration is subsequently titrated according to the target MAC value. Anesthesia depth and oxygenation are monitored using PSI monitoring and serial arterial blood gas measurements.

Sponsors & Collaborators

  • Erzincan Binali Yildirim Universitesi

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-03-01
Primary Completion
2026-07-01
Completion
2026-08-01

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07534839 on ClinicalTrials.gov