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Preoperative Topical Lidocaine Versus Intravenous Fentanyl to Obtund the Stress of Intubation Under Anesthesia.

NCT07533643 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2026-04-16

No results posted yet for this study

Summary

To compare the effectiveness of preoperative combined topical airway anesthesia consisting of nebulised, mouth rinsing and gargling with lidocaine versus intravenous fentanyl to prevent the stress of endotracheal intubation by direct laryngoscopy under general anesthesia.

Conditions

  • Hemodynamics After Endotracheal Intubation

Interventions

DRUG

topical lidocaine

topical lidocaine nebulized for 10 min + mouth rinsing and gargling for 3 min

DRUG

Fentanyl (Low Dose)

low dose fentanyl iv 1 mic per kg before induction

Sponsors & Collaborators

  • Kasr El Aini Hospital

    lead OTHER

Principal Investigators

  • Mohamed Ahmed Mansour, professor · Cairo University

  • Shady Rady Abdalla, lecturer · Cairo University

  • sherif Ismail Muhammed, lecturer · Cairo University

  • Zeinab Mohammed Gamal, Resident · Cairo University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-08-01
Primary Completion
2025-09-20
Completion
2025-11-15

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07533643 on ClinicalTrials.gov