Blood Viscosity and Outcomes After Elective Craniotomy
NCT07530393 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000
Last updated 2026-04-15
Summary
This prospective observational study aims to evaluate the association between intraoperative blood viscosity and postoperative clinical outcomes in adult patients undergoing elective intracranial craniotomy.
Blood viscosity is an important determinant of microcirculatory flow and cerebral perfusion, but its role in perioperative outcomes remains unclear. In this study, intraoperative blood viscosity and related hematologic parameters will be measured, and their relationships with cerebral oxygenation and postoperative complications will be analyzed.
The study will enroll adult patients undergoing elective intracranial surgery at a single tertiary center. The findings of this study may improve understanding of perioperative hemodynamic and hemorheological factors and help identify potential risk markers for adverse postoperative outcomes.
Conditions
- Postoperative Complications
- Intracranial Surgery
Interventions
- OTHER
-
Observational Assessment of Blood Viscosity
No intervention is assigned. Intraoperative blood viscosity and clinical variables are measured as part of routine care and analyzed for association with postoperative outcomes.
Sponsors & Collaborators
-
Asan Medical Center
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-05-01
- Primary Completion
- 2029-12-31
- Completion
- 2030-03-31
Countries
- South Korea
Study Locations
More Related Trials
-
The Effect of Pneumoperitoneum and Trendelenburg Position on Intracranial Pressure: Ultrasonographic Measurement of Optic Nerve Sheath Diameter
NCT01641302 ·Status: COMPLETED
-
Association Between EEG Changes and Hormonal Response to Tracheal Intubation and Surgical Stimulation
NCT06228729 ·Status: COMPLETED
-
Changes of Right and Left Cerebral Oxygen Saturation and Blood Flow During Nephrectomy in Lateral Decubitus Position
NCT01101490 ·Status: COMPLETED
-
Role of Cerebral Oximetry in Reducing Postoperative End Organ Dysfunction/Failure After Complex Non-Cardiac Surgery
NCT04627506 ·Status: UNKNOWN ·Phase: NA
-
Effect of Preemptive Low Dose Norepinephrine Infusion on Intraoperative Hemodynamic Stability and Postoperative Outcomes in Patients Undergoing Brain Tumor Resection With a Craniotomy
NCT05814601 ·Status: UNKNOWN ·Phase: NA
-
Registry Construction for Perioperative Data in Patients Undergoing Cardiovascular Surgery
NCT04136210 ·Status: COMPLETED
-
Intraoperative Heart Rate Thresholds and Postoperative Mortality
NCT07075744 ·Status: COMPLETED
-
Arterial Pressure and Surgical Hemostasis in Elective Neurosurgery.
NCT05874050 ·Status: COMPLETED
-
The Safety and Efficacy of Peri-procedure Blood Pressure Management of Revascularization
NCT03256513 ·Status: UNKNOWN ·Phase: NA
-
Performance and Safety of I-020805 in Prevention of Cerebrospinal Fluid (CSF) Leakage Following Elective Craniotomy
NCT01295619 ·Status: COMPLETED ·Phase: NA
-
Cerebral Perfusion Variation During Blood Pressure Changes in ICU
NCT05804773 ·Status: RECRUITING
-
Observational Study on the Clinical Impact of Desaturation During Liver Surgery
NCT01458262 ·Status: COMPLETED
-
Vasodilator-induced Hypovolemia in Living Liver Donors
NCT02033967 ·Status: COMPLETED ·Phase: NA
-
Prospective Observational Multimodal Neuromonitoring During High-Risk Adult Surgery
NCT07577726 ·Status: NOT_YET_RECRUITING
-
Impact of Intravascular Fluid Resuscitation and Whole Blood Viscosity for Cardiac Surgery
NCT02757118 ·Status: UNKNOWN ·Phase: NA
-
Prospective Validation of DL Model for Postoperative MACCE Prediction
NCT07054502 ·Status: NOT_YET_RECRUITING
-
The Effect of Restrictive Fluid and Vasopressin During Surgery of Burn Patients
NCT03590873 ·Status: UNKNOWN ·Phase: NA
-
Role of Absolute Cerebral Oximetry to Prevent Neurocognitive Injury in Elderly Patients Undergoing Cardiac Surgery
NCT00991328 ·Status: TERMINATED ·Phase: PHASE3
-
Arterial Waveform Analysis for Predicting Post-induction Hypotension
NCT05756933 ·Status: UNKNOWN
-
Assessing Cerebral Blood Flow Autoregulation During Surgery in the Head-up Position
NCT01225185 ·Status: COMPLETED
-
Measurement of Cerebral Flow Using Transfontanellar Doppler in Infants Under Cardiopulmonary Bypass
NCT01996020 ·Status: COMPLETED
-
Intraoperative Estimated Blood Loss, Blood Transfusion, and Postoperative Clinical Outcomes in Patients Undergoing Non Cardiac Surgery, Siriraj Hospital
NCT05430659 ·Status: ACTIVE_NOT_RECRUITING
-
Cerebral Perfusion During Induction of General Anesthesia
NCT03769142 ·Status: COMPLETED
-
Association of Intraoperative Hemodynamic Characteristics to Postoperative Complications and Mortality
NCT06355362 ·Status: NOT_YET_RECRUITING
-
Perioperative Blood Transfusion in Open Liver Resection
NCT06189911 ·Status: COMPLETED