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Effect of Sciatic Nerve Mobilization on Lower Extremity Pain Perception

NCT07525895 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 34

Last updated 2026-04-27

No results posted yet for this study

Summary

This randomized controlled study aims to investigate the effect of sciatic nerve mobilization on pain perception in lower extremity peripheral nerves, specifically the tibial and common peroneal nerves. The study will be conducted in university students at Fenerbahçe University. Participants will be randomly assigned to either an intervention group or a control group.

Pressure pain threshold (PPT) will be measured using a pressure algometer at standardized anatomical points over the tibial and common peroneal nerves before and after the intervention period. Demographic and clinical information, including age, sex, height, weight, dominant lower extremity, physical activity level, history of lower extremity injury or surgery, neurological or systemic disease, and regular medication use, will also be recorded.

Participants in the intervention group will receive a standardized sciatic nerve mobilization protocol consisting of sliding-type neurodynamic mobilization performed in the supine position, including components of hip flexion, knee extension, and ankle dorsiflexion/plantarflexion in a rhythmic sequence. No intervention will be applied to the control group. The primary purpose of the study is to determine whether sciatic nerve mobilization changes pressure pain threshold values in the tibial and common peroneal nerves compared with no intervention.

Conditions

  • Sciatic Nerve
  • Lower Extremity Pain

Interventions

OTHER

Sciatic Nerve Mobilization

A standardized sliding-type sciatic nerve mobilization will be applied in the supine position. The technique includes coordinated hip flexion, knee extension, and ankle dorsiflexion/plantarflexion movements to produce a sliding effect on the sciatic nerve.

Sponsors & Collaborators

  • Fenerbahce University

    lead OTHER

Principal Investigators

  • Sümeyye Akçay, Asst. Prof. · Fenerbahçe University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-03-20
Primary Completion
2026-05-31
Completion
2026-05-31

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07525895 on ClinicalTrials.gov