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Investigation of the Relationship Between Central Sensitization and Neuropathic Pain in Lumbar Disc Herniation

NCT06269068 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 180

Last updated 2024-02-21

No results posted yet for this study

Summary

Central sensitization (CS) is as increased response to normal or sub-threshold stimuli of central nervous system and its close relationship with in many musculoskeletal diseases with chronic pain has been demonstrated in several studies. CS is also one of the main mechanisms proposed in the generation of neuropathic pain, and the relationship between pain sensitization and neuropathic complaints has been shown in different diseases.In this study, it was aimed to investigate the effect of central sensitization on the distribution pattern and neuropathic character of pain in patients with lumbar disc herniation who applied to the physical medicine and rehabilitation outpatient clinic.

Conditions

  • Central Sensitisation

Interventions

DIAGNOSTIC_TEST

Central sensitization inventory

Standardized questionnaire to determine the level of central sensitization. Patients with a score of 40 and above are considered to have central sensitization.

OTHER

Short form-36

Standardized questionnaire to investigate the quality of life in patients. The score of the scale is between 0-100. The higher scores are associated with greater deterioration in quality of life.

OTHER

Oswestry Low Back Pain Disability Questionnaire

With this scale, it is questioned to what extent the patient is affected by low back pain in selected daily living activities under certain ten headings. In total scoring, disability is expressed as a percentage, and high scores are interpreted in favor of an increase in disability.

OTHER

Douleur Neuropathique 4

The questionnaire consists of 10 items; while the nature of pain is questioned in 7 items, the other 3 items include brief sensory examination. Patients with a score of 4 or more out of 10 are considered to have neuropathic pain.

OTHER

Visual analogue scale

global pain score on a 0 to 10

Sponsors & Collaborators

  • Marmara University

    lead OTHER

Principal Investigators

  • Canan Şanal Toprak, Asst.Prof · Marmara University

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-01-16
Primary Completion
2024-04-10
Completion
2024-06-01

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06269068 on ClinicalTrials.gov