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Prospective Randomized Trial Comparing Longitudinal vs. Transverse A1 Pulley Release

NCT07516652 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 200

Last updated 2026-04-08

No results posted yet for this study

Summary

The goal of this clinical trial is to compare two different skin incisions used in surgery to treat trigger finger in adult patients. Trigger finger occurs when a finger gets stuck or locks because of swelling of the sheath around the tendons the help move the fingers. The main questions it aims to answer are (1) Does the type of skin cut affect how well the hand works 6 weeks after surgery? (2) Does the type of skin cut affect pain levels, scar healing, and how quickly people return to their normal activities? Orthopaedic surgeons will compare a straight incision along the finger (longitudinal incision) to a incision across the crease in the palm (transverse incision) to see if one type of incision results in better recovery, less pain, a better scar, and higher patient satisfaction with the procedure. Participants who have trigger finger and are indicated for surgery will have surgery to release the pulley in their finger using one of the two types of incisions (assigned by chance). Participants will fill out questionnaires about their hand function and pain before surgery and at follow-up visits. Participants will have their scar checked and rated at about 2, 6, and 12 weeks after surgery, and report on their pain for the first few days after surgery and when they can return to work and move their finger without pain.

Conditions

  • Trigger Finger
  • Stenosing Tenosynovitis

Interventions

PROCEDURE

Open A1 Pulley Release

Surgical release of the first annular (A1) pulley to treat stenosing tenosynovitis (trigger finger). Participants receive either a longitudinal or transverse incision based on their randomized arm assignment. All other aspects of surgical technique and post-operative care are standardized.

Sponsors & Collaborators

  • University of Chicago

    collaborator OTHER

  • Washington University School of Medicine

    lead OTHER

Principal Investigators

  • Jason Strelzow, MD · Associate Professor, Orthopaedic Surgery Division of Hand and Microsurgery, Washington University in St Louis

  • Ryan Calfee, MD · Professor, Orthopaedic Surgery Division of Hand and Microsurgery Chief, Hand and Microsurgery Service Medical Director, Washington University and Barnes-Jewish Orthopedic Center

  • Nisha N Kale, MD · Washington University in St. Louis Department of Orthopaedic Surgery

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-04-01
Primary Completion
2027-04-01
Completion
2028-03-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07516652 on ClinicalTrials.gov