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Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma

NCT07506239 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2026-04-01

No results posted yet for this study

Summary

This study aims to evaluate the efficacy of Laser Interstitial Thermal Therapy (LITT) in treating recurrent or progressive, low-grade gliomas (LGG) in pediatric, adolescent and young adult patients.

Conditions

  • Low-grade Glioma
  • Recurrent Low Grade Glioma
  • Low Grade Glioma of Brain
  • Pediatric Cancer

Interventions

DEVICE

Laser Interstitial Thermal Therapy (LITT)

Perform ablation using LITT

PROCEDURE

Magnetic resonance imaging (MRI)

Undergo single imaging procedure

OTHER

Questionnaires

Participants will complete questionnaires

Sponsors & Collaborators

Principal Investigators

  • Sabine Mueller, MD, PhD · University of California, San Francisco

  • Margaret Shatara · Children's Minnesota

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
2 Years
Max Age
25 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-03-25
Primary Completion
2030-01-01
Completion
2031-01-01
FDA Device
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07506239 on ClinicalTrials.gov