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Heart Problems in Children With Chronic Liver Disease

NCT07502196 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2026-03-30

No results posted yet for this study

Summary

Chronic liver disease (CLD) in children can sometimes lead to complications in other parts of the body, including the heart. The primary purpose of this observational study is to assess the presence and type of cardiac problems in children who have been diagnosed with chronic liver disease.

Researchers will observe children under the age of 18 who are receiving care at the gastroenterology and hepatology unit at Assiut University Children Hospital. Participants will undergo standard medical evaluations to check both their liver and heart health.

These evaluations include:

* A detailed medical history and thorough physical examination
* Routine blood tests to check liver function, kidney function, coagulation, and electrolytes
* Abdominal imaging, such as an ultrasound, to look at the liver.
* An electrocardiogram (ECG) to check the heart's electrical activity and rhythm, including measuring the QTc interval.
* An echocardiogram to look at the structure of the heart and check how well its chambers and valves are functioning.

The study aims to identify specific heart conditions that can be associated with severe liver disease, such as portopulmonary hypertension, cirrhotic cardiomyopathy (changes in the heart muscle's function), and electrical repolarization abnormalities. Children who already have known congenital heart disease or a history of other heart problems will not be included in the study.

Conditions

  • Chronic Liver Disease (CLD)
  • Liver Cirrhosis
  • Cardiac Abnormalities
  • Portopulmonary Hypertension
  • Cirrhotic Cardiomyopathy

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Eligibility

Max Age
17 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-04-30
Primary Completion
2027-04-30
Completion
2027-05-31

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Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07502196 on ClinicalTrials.gov