MedTrace Logo

Liver Disease in Pregnancy

NCT03834285 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2020-03-27

No results posted yet for this study

Summary

Liver Diseases in pregnancy represents rare disorders and current data is derived primarily from single centres and retrospective cohorts. Moreover, the population prevalence of these diseases is low and to-date, it has proven difficult to generate reliable data at a patient level.

This is a multi-center, prospective cohort study that will open at 3 centers within the UK; and 4 centers in the European Union. The investigators will aim to collect data and blood samples at various time points, for patients presenting with liver disease during pregnancy. The main rationale behind this study is to establish a platform that enables detailed review of the outcomes of these rare diseases; to help classify and stratify patients according to risk and develop interventional studies and care pathways to improve overall outcome.

Conditions

  • Pregnancy Disease
  • Cirrhosis, Liver
  • HELLP Syndrome
  • AFLP - Acute Fatty Liver of Pregnancy
  • Intrahepatic Cholestasis of Pregnancy

Sponsors & Collaborators

  • European Association for the Study of the Liver

    collaborator UNKNOWN

  • King's College Hospital NHS Trust

    lead OTHER

Principal Investigators

  • Michael Heneghan · King's College Hospital NHS Trust

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-05-09
Primary Completion
2024-04-08
Completion
2025-04-08

Countries

  • United Kingdom

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03834285 on ClinicalTrials.gov