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Analgesic Equivalence of NSAIDs and Tramadol in Acute Postoperative Pain Following Minimally Invasive Surgery

NCT07500454 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2026-05-15

No results posted yet for this study

Summary

This pilot randomised controlled trial compared the analgesic equivalence of three intravenous premedication regimens - tramadol 150 mg, ketorolac 60 mg, and diclofenac 150 mg - in adult patients undergoing elective minimally invasive surgery under balanced general anaesthesia. The primary outcome was postoperative pain intensity measured using the Numerical Rating Scale (NRS 0-10) at recovery room arrival and at 30, 60, and 90 minutes thereafter.

Conditions

  • Postoperative Pain
  • Acute Pain

Interventions

DRUG

Tramadol

Tramadol 150 mg IV, single dose, administered in 100 mL 0.9% saline 45 minutes before skin incision.

DRUG

Ketorolac

Ketorolac 60 mg IV, single dose, administered in 100 mL 0.9% saline 45 minutes before skin incision.

DRUG

Diclofenac

Diclofenac 150 mg IV, single dose, administered in 100 mL 0.9% saline 45 minutes before skin incision.

Sponsors & Collaborators

  • ISSSTE Hospital Regional "Gral. Ignacio Zaragoza"

    lead OTHER_GOV

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-06-20
Primary Completion
2024-07-23
Completion
2024-07-26

Countries

  • Mexico

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07500454 on ClinicalTrials.gov