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Er,Cr:YSGG Laser Versus Conventional Preparation for Minimally Invasive Caries Removal

NCT07493278 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 32

Last updated 2026-03-30

No results posted yet for this study

Summary

This study compared two standard methods for minimally invasive caries removal in children: conventional mechanical excavation and Er,Cr:YSGG laser preparation. The study aimed to evaluate the reduction of Streptococcus mutans and Lactobacillus spp. in dentin using PCR analysis. All procedures were performed as part of routine dental care, and written informed consent was obtained from parents or legal guardians.

Conditions

  • Dental Caries

Interventions

PROCEDURE

Mechanical Caries Removal

Participants received conventional mechanical caries removal according to standard pediatric dentistry protocols. Laboratory personnel analyzing PCR results were blinded to group assignments.

PROCEDURE

Er,Cr:YSGG Laser Caries Removal

Participants received caries removal using the Er,Cr:YSGG laser (2780 nm) according to manufacturer-recommended parameters for minimally invasive dentin excavation. Laboratory personnel analyzing PCR results were blinded to group assignments

Sponsors & Collaborators

  • European Union Next Generation

    collaborator UNKNOWN

  • Medical University of Sofia

    lead OTHER

Principal Investigators

  • Natalia Grancharova, MD, PhD · Medical University Sofia

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
8 Years
Max Age
15 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-10-23
Primary Completion
2026-02-04
Completion
2026-02-04

Countries

  • Bulgaria

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07493278 on ClinicalTrials.gov