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Building Adaptive School-based Interventions for Caries

NCT07265830 · Status: NOT_YET_RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 1200

Last updated 2026-03-02

No results posted yet for this study

Summary

Dental caries (tooth decay) is the world's most prevalent noncommunicable disease. Current preventive and therapeutic treatments are available that can be provided in a school-based health service environment. However, not all children respond to care, and school programs can result in under- or over-treatment, leaving children at high risk. The Building Adaptive School-based Interventions for Caries (BASICS) study will identify the optimal sequence and intensity of these treatments to minimize nonresponse, creating adaptive interventions tailored to specific needs in order to personalize school-based dental medicine.

Conditions

  • Dental Caries

Interventions

DEVICE

Silver Diamine Fluoride (38%)

Topically applied silver diamine fluoride 38% solution

DEVICE

Glass Ionomer Sealant

GIC Dental Sealants

DEVICE

Fluoride Varnishes

Topically applied fluoride varnish (FV)

BEHAVIORAL

Hygiene Intervention

Behavioral intervention to improve dental hygiene

Sponsors & Collaborators

Principal Investigators

  • Ryan R Ruff, PhD, MPH · New York University College of Dentistry/Epidemiology

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
5 Years
Max Age
13 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-09-30
Primary Completion
2030-06-30
Completion
2030-06-30
FDA Device
Yes

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07265830 on ClinicalTrials.gov