Image Guided Genicular Nerve Radiofrequency Ablation for Chronic Knee Osteoarthritis

NCT07475793 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 52

Last updated 2026-03-27

No results posted yet for this study

Summary

The goal of this prospective randomized control trial is to provide continued pain relief, classically long-lasting 3 to12 months, and enhanced function in patients following: both gender; male and female, age group; \>50yr, healthy volunteers along with Radiographic diagnosis of knee OA with KL grade 3 and 4 in addition of Chronic knee pain ≥ 6 months and patients with ≥50% decrease in pain strength after diagnostic genicular nerve block. The main question it aims to answer is:

Is ultrasound-guided genicular nerve RFA more efficient in lowering pain intensity at six months contrasted with fluoroscopic guided method in patients with chronic knee osteoarthritis? Researchers will compare Group A (Fluoroscopic) to Group B (Ultrasound) to see comparison in efficiency of ultrasound guided against fluoroscopic guided genicular nerves block for decrease in pain intensity and functional improvement.

Conditions

  • Chronic Knee Osteoarthritis

Interventions

PROCEDURE

Ultrasound Guided

Genicular nerves radiofrequency ablation will be done with the help of ultrasound guidance.

PROCEDURE

Fluoroscope Guided

Control group in which genicular nerves radiofrequency ablation will be done with the help of fluoroscopic guidance.

Sponsors & Collaborators

  • Aga Khan University

    lead OTHER

Principal Investigators

  • Ali Sarfraz Siddiqui, MBBS-FCPS · Aga Khan University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-05-01
Primary Completion
2027-04-30
Completion
2027-05-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07475793 on ClinicalTrials.gov