Total Knee Arthroplasty in Conjunction With Intra-operative Genicular Nerve Radio-Frequency Ablation
NCT07381062 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 70
Last updated 2026-02-11
Summary
The aim of this study is to compare between conventional Total Knee Arthroplasty (TKA) and Total Knee Arthroplasty (TKA) combined with intra-operative Genicular Nerve Radio-Frequency Ablation (GNRFA), concerning post-operative functional outcome and pain scores in patients with advanced knee osteoarthritis
Conditions
- Post Operative Pain
- Functional Outcome
Interventions
- PROCEDURE
-
Total knee arthroplasty
Conventional Total knee arthroplasty operation performed
- PROCEDURE
-
Genicular nerve radiofrequency ablation
Genicular nerve radiofrequency ablation done with no modifications except being performed with total knee arthroplasty in the same setting
Sponsors & Collaborators
-
Ain Shams University
lead OTHER
Principal Investigators
-
Assem Mohamed Mahmoud Ahmed, MD · Ain Shams University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 50 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-02-22
- Primary Completion
- 2024-03-04
- Completion
- 2024-10-01
Countries
- Egypt
Study Locations
More Related Trials
-
Thermal Radiofrequency Neurolysis Versus Alcoholic Neurolysis of the Genicular Nerves for Treatment of Chronic Knee Pain in Advanced Knee Osteoarthritis
NCT07125768 ·Status: COMPLETED ·Phase: NA
-
Genicular Nerve Phenol Neurolysis Versus Radiofrequency Ablation for Pain Relief in Grade 4 Knee Osteoarthritis
NCT06864390 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Radiofrequency Applications and Alcoholic Neurolysis of Genicular Nerve for the Treatment of Knee Osteoarthritic Pain
NCT06520384 ·Status: COMPLETED ·Phase: NA
-
Synovectomy in Primary Total Knee Arthrplasty
NCT03778463 ·Status: UNKNOWN ·Phase: NA
-
Transcutaneous Pulsed Radiofrequency Application Plus Genicular Nerve Block Versus Intraarticular Hyaluronic Acid Injection for Management of Chronic Pain in Knee Osteoarthritis.
NCT06710782 ·Status: COMPLETED ·Phase: NA
-
The Effect of RF Genicular Nerve Block Applied in the Preoperative Period on Fast-track Total Knee Arthroplasty
NCT06239649 ·Status: RECRUITING
-
Comparative Study of CT and Fluoroscopic Guided Genicular Nerve Ablation in the Treatment of Knee Osteoarthritis
NCT06514703 ·Status: RECRUITING ·Phase: NA
-
Assessing Function and Pain After Total Knee Arthroplasty With Combined Femoral and Popliteal Nerve Block
NCT06196359 ·Status: COMPLETED ·Phase: NA
-
Comparative Effectiveness of Genicular Nerve Radiofrequency Thermocoagulation and Intra-Articular Pulsed Radiofrequency in the Management of Knee Osteoarthritis Pain
NCT07098455 ·Status: COMPLETED ·Phase: NA
-
Radio-frequency Ablation in Knee Osteoarthritis by Three Needles Technique
NCT03613610 ·Status: UNKNOWN ·Phase: NA
-
Ultrasound-guided Radiofrequency Ablation of the Genicular Nerve Versus Physical Therapy for Chronic Knee Osteoarthritis
NCT06173830 ·Status: RECRUITING ·Phase: NA
-
Comparative Study Between Intra Articular Injection of Hyaluronic Acid (HA) With Platelet Rich Plasma (PRP) Versus Genicular Nerve Thermal Radiation in Management of Pain in Knee Osteoarthritis
NCT04188561 ·Status: COMPLETED ·Phase: PHASE4
-
Functional Outcome and Analgesia in TKA: Radiofrequency vs Continuous Adductor Canal Block
NCT02680392 ·Status: COMPLETED ·Phase: NA
-
Monopolar Versus Biopolar Radiofrequency in OA Knee Pain
NCT05591768 ·Status: COMPLETED ·Phase: NA
-
Function and Pain Following Knee Replacement
NCT05478005 ·Status: COMPLETED ·Phase: NA
-
Comparison of Conventional and Cooled Radiofrequency Ablation in Knee Osteoarthritis
NCT06863181 ·Status: COMPLETED ·Phase: NA
-
Sequential Genicular Nerve Ablation Prior to Geniculate Artery Embolization in Knee Pain
NCT06514755 ·Status: RECRUITING ·Phase: NA
-
Percutaneous vs Conventional Radiofrequency Applications for the Treatment of Knee Osteoarthritic Pain
NCT06520371 ·Status: COMPLETED ·Phase: NA
-
Genicular Nerve and Intra-articular Radiofrequency Versus Platelet Rich Plasma Injection for Knee Osteoarthritis
NCT03379883 ·Status: UNKNOWN ·Phase: NA
-
Does Radiofrequency Ablation of the Articular Nerves of the Knee Prior to Total Knee Replacement Improve Pain Outcomes
NCT02746874 ·Status: COMPLETED ·Phase: NA
-
Efficacy of Ultrasound-Guided Genicular Nerve Radiofrequency Ablation Therapy
NCT06914960 ·Status: RECRUITING ·Phase: NA
-
Genicular RFT vs Phenol Management in Patients With Knee Osteoarthritis
NCT05908942 ·Status: UNKNOWN
-
Saphenous Nerve Radiofrequency for Knee Osteoarthritis Trial
NCT02826850 ·Status: UNKNOWN ·Phase: PHASE3
-
Phenol Neurolysis and Radiofrequency Thermocoagulation in Knee Arthroplasty Surgery
NCT07381335 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Efficacy of Genicular Nerve Radiofrequency
NCT04100707 ·Status: UNKNOWN ·Phase: NA