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SUPPORT+ Digital Self-Management and Clinical Support for Advanced Cancer

NCT07475312 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 633

Last updated 2026-04-02

No results posted yet for this study

Summary

The goal of this clinical trial is to learn whether SUPPORT+, a digital symptom monitoring and self-management mobile application, can improve health-related quality of life and clinical outcomes in adults with advanced cancer receiving palliative care.

The main questions this study aims to answer are:

* Does use of SUPPORT+ help maintain or improve health-related quality of life compared with usual palliative care?
* Does SUPPORT+ reduce functional decline and acute health care use, such as hospitalisations, compared with usual care?

Researchers will compare patients using the SUPPORT+ mobile application with patients receiving usual palliative care to see if digital symptom monitoring combined with automated self-management guidance and nurse follow-up improves patient-reported and clinical outcomes.

Participants assigned to the SUPPORT+ arm will:

* Use the SUPPORT+ mobile application for weekly symptom reporting using the Integrated Palliative Care Outcome Scale (IPOS)
* Receive automated self-management advice based on reported symptoms
* Receive follow-up contact from a nurse when severe or concerning symptoms are identified
* Continue to receive usual palliative care throughout the study period

Participants assigned to the usual care arm will:

* Receive usual palliative care provided by their clinical team
* Complete study assessments at scheduled time points
* Not receive digital symptom monitoring, automated self-management advice, or nurse follow-up through the SUPPORT+ application

Conditions

Interventions

BEHAVIORAL

SUPPORT+ Digital Symptom Monitoring and Clinical Support

SUPPORT+ is a mobile application that prompts participants to complete weekly symptom reporting using the Integrated Palliative Care Outcome Scale (IPOS). After each submission, the application provides automated, symptom-specific self-management advice. Reports indicating severe symptoms trigger real-time alerts to palliative care nurses, who contact participants during office hours to provide clinical guidance, including medication advice, self-management strategies, expedited clinic review, or recommendations for urgent medical care when appropriate. Participants may also initiate nurse contact through the application during office hours.

Sponsors & Collaborators

  • The University of Hong Kong

    lead OTHER

Principal Investigators

  • Wing-Lok Wendy Chan, MBBS · The University of Hong Kong

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-01-16
Primary Completion
2026-12-31
Completion
2026-12-31

Countries

  • Hong Kong

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07475312 on ClinicalTrials.gov