Combined Systemic and Intraperitoneal Chemotherapy for Synchronous Gastric and/or Gastroesophageal Peritoneal Carcinomatosis
NCT07475286 · Status: NOT_YET_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 22
Last updated 2026-03-16
Summary
This trial will administer laparoscopic hyperthermic intraperitoneal chemotherapy (HIPEC) to patients with peritoneal carcinomatosis from gastric cancer (GPC) who are receiving standard of care systemic chemotherapy.
Conditions
- Synchronous Gastric Peritoneal Carcinomatosis
- Gastroesophageal Peritoneal Carcinomatosis
Interventions
- DRUG
-
Cisplatin interferes with DNA replication, which kills the fastest proliferating cells.
- DRUG
-
Mitomycin C
A drug that slows down the growth of cancer cells by making them less able to create the DNA, RNA, and proteins they need to multiply.
Sponsors & Collaborators
-
Dr. Samer AlMasri, MD
collaborator UNKNOWN -
Mohammad Haroon Asif Choudry
lead OTHER
Principal Investigators
-
Haroon Choudry, MBBS, FACS · UPMC Hillman Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-04-30
- Primary Completion
- 2030-04-30
- Completion
- 2034-04-30
- FDA Drug
- Yes
Countries
- United States
Study Locations
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