MedTrace Logo

Role of High-Frequency Oscillations on Scalp EEG in Identifying Epileptogenic Activity in Patients With Epilepsy and Healthy Controls

NCT07470931 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2026-03-13

No results posted yet for this study

Summary

This observational case-control study aims to evaluate whether high-frequency oscillations (HFOs) detected on scalp electroencephalography (EEG) can differentiate patients with epilepsy from healthy controls. A signal-processing algorithm was developed to identify HFO activity in scalp EEG recordings, with particular focus on ripple (80-250 Hz) and fast ripple (250-500 Hz) frequency bands. Scalp EEG recordings obtained from patients with epilepsy and healthy controls are analyzed after preprocessing and filtering steps. The main outcome is the mean residence time of HFO-related activity above a predefined threshold in the ripple and fast ripple bands. The study investigates whether this noninvasive EEG-based approach may provide a useful biomarker for epilepsy diagnosis.

Conditions

  • Epilepsies

Sponsors & Collaborators

  • Saglik Bilimleri Universitesi

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-03-01
Primary Completion
2023-09-30
Completion
2023-09-30

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07470931 on ClinicalTrials.gov