MedTrace Logo

Bupivacaine Alone vs Bupivacaine With Tramadol in Local Anesthesia Procedures

NCT07469826 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2026-03-13

No results posted yet for this study

Summary

This study looked at two different medicines used during local anesthesia to control pain after surgery. Investigators compared bupivacaine alone with bupivacaine mixed with tramadol. Both medicines are commonly used to numb the surgical area and reduce pain.

The investigators included 100 adult patients who had minor surgeries under local anesthesia. Half received only bupivacaine, and the other half received bupivacaine combined with tramadol. After surgery, patients were asked to rate their pain at 4, 8, and 24 hours.

The results showed that patients who received bupivacaine with tramadol felt less pain, especially at 24 hours after surgery, compared to those who received bupivacaine alone.

In simple words:

Adding tramadol to bupivacaine helps reduce pain better than bupivacaine alone.

This method may help patients recover faster, feel more comfortable, and need fewer pain medicines after surgery.

Conditions

  • Post Operative Pain, Acute

Interventions

DRUG

Tramadol

A single dose of 1 mg/kg tramadol at the surgical site

DRUG

Bupivacaine

Single dose 0.5 ml/kg of 0.25% Bupivacaine at surgical site

Sponsors & Collaborators

  • Jinnah Sindh Medical University

    collaborator OTHER

  • Jinnah Postgraduate Medical Centre

    lead OTHER_GOV

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-10-10
Primary Completion
2023-04-10
Completion
2023-05-10

Countries

  • Pakistan

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07469826 on ClinicalTrials.gov