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Lifestyle Interventions to Prevent cOgnitive Deficits in Subjects With Depressive Symptoms: From mEchanisms to Clinical pRactice

NCT07462013 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2026-06-17

No results posted yet for this study

Summary

POWER project is a randomized, controlled, non-profit study with the primary objective of testing the effectiveness of non-pharmacological interventions-such as physical activity, cognitive training, and dietary supplementation-in reducing depressive symptoms and preventing or delaying cognitive impairments that frequently co-occur in individuals with Major Depressive Disorder (MDD).

Conditions

  • Major Depressive Disorder (MDD)

Interventions

DIETARY_SUPPLEMENT

Soybean oil (Standard treatment)

3g/day of Soybean Oil

DIETARY_SUPPLEMENT

Eicosapentaenoic acid (omega-3 fatty acid)

3 grams/day

Sponsors & Collaborators

  • IRCCS Centro San Giovanni di Dio Fatebenefratelli

    collaborator OTHER

  • University College Cork

    collaborator OTHER

  • National Science and Technology Council, Taiwan

    lead OTHER_GOV

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
50 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-10-01
Primary Completion
2028-06-30
Completion
2028-09-30

Countries

  • Taiwan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07462013 on ClinicalTrials.gov