Westlake Frequent-sampling Cohort
NCT07460687 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 20
Last updated 2026-03-10
Summary
This intensive longitudinal study investigates the day-to-day stability and natural fluctuations of the gut microbiome in healthy adults over a 15-day period. While the human gut microbiome is a complex ecosystem, its baseline stability in the absence of disease or medical intervention remains insufficiently characterized due to low sampling frequency in prior research. By recruiting healthy volunteers for continuous daily sampling, this study aims to map temporal community structures and evaluate the stability of core microbiota. Additionally, the research utilizes Continuous Glucose Monitoring (CGM) to explore the potential relationships between microbiome dynamics, daily dietary intake, and host glycemic stability.
Conditions
- Health Adults
- Stability of Microbiome
Sponsors & Collaborators
-
Westlake University
lead OTHER
Principal Investigators
-
Ju-Sheng Zheng, PhD · Westlake University
Eligibility
- Min Age
- 18 Years
- Max Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2026-04-08
- Primary Completion
- 2027-04-08
- Completion
- 2027-12-31
Countries
- China
Study Locations
More Related Trials
-
Implications of the Human Microbiota for Health and Disease
NCT04203303 ·Status: RECRUITING
-
Feasibility Studies to Inform Novel Proposals to Avert Community-Based Antimicrobial Resistance Spread
NCT02666274 ·Status: UNKNOWN
-
Gut Microbiota Pilot Study
NCT03897023 ·Status: UNKNOWN
-
Gut Microbiota Pilot Study
NCT03892590 ·Status: UNKNOWN
-
Gut Microbiota in Patients With Limb Lymphedema and Recurrent Lymphangitis
NCT06228937 ·Status: RECRUITING
-
Comparison of Gut Microbiota in Sedentary and Active Women
NCT02901912 ·Status: COMPLETED
-
Identification of Gut Microbiome Biomarkers Associated to Acquisition of Enterobacteriae Highly Resistant to Third Generation Cephalosporines Following Ceftriaxone Treatment.
NCT03569917 ·Status: TERMINATED ·Phase: NA
-
Microbiota Study in Liver Transplanted Patients
NCT03507140 ·Status: COMPLETED
-
Pre-analytical Processing of Human Samples for Microbiota Analysis Quality
NCT07452965 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
PRObing The Efficacy of Commercial Stage Storage Buffers and Evaluating Gut Metaproteome Variability Between Individuals
NCT06423508 ·Status: RECRUITING
-
Acute Intestinal Failure in Critically Ill Patients and Microbial Translocation
NCT03861325 ·Status: COMPLETED
-
Enteric Microbiome and Liver Transplantation
NCT03666312 ·Status: UNKNOWN
-
Pathogen-microbiome Interaction During Helicobacter Pylori Infection
NCT05121025 ·Status: RECRUITING
-
Human Microbiota and Liver Transplant
NCT02223468 ·Status: COMPLETED
-
Phages Dynamics and Influences During Human Gut Microbiome Establishment
NCT03296631 ·Status: TERMINATED
-
Surgical Site Infections and the Microbiome: Understanding the Pathogenesis of Surgical Site Infections
NCT06300892 ·Status: RECRUITING
-
Baseline Study of Vaginal Microbiota in Healthy Chinses Female Population
NCT04887636 ·Status: COMPLETED
-
Prevalence of Digestive Carriage of Integrons
NCT01985217 ·Status: COMPLETED
-
The Urinary Microbiome and Its Relationship to the Urinary and Serum Metabolome in Healthy Peri- and Postmenopausal Women
NCT06573827 ·Status: NOT_YET_RECRUITING
-
Human Skin and Gut Mycobiome and Bacteriome Comprehensive Registry
NCT05196061 ·Status: RECRUITING
-
Intestinal Microbiota Composition After Antibiotic Treatment in Early Life
NCT02536560 ·Status: UNKNOWN
-
Hepatitis E Infection : Emergence Mechanisms in North-Eastern France of Polymorphic Clinical Forms.
NCT03524014 ·Status: UNKNOWN
-
Effect of Antibiotics on Gut Microbiome and Plasma Metabolome
NCT03273296 ·Status: COMPLETED ·Phase: PHASE4
-
Antibiotic Exposure on Gut Microbiota and Motility Establishment in Newborns
NCT06850896 ·Status: ACTIVE_NOT_RECRUITING
-
Integrated Genetic and Functional Analysis of the Female Microbiome in a Flemish Cohort
NCT04319536 ·Status: UNKNOWN