Single-dose Pharmacokinetics of Pociredir in Participants With Sickle Cell Disease

Safety, Pharmacokinetic, and Pharmacodynamic Study of NKTT120 in Adult Patients With Stable Sickle Cell Disease (SCD)

NCT01783691 ·Status: COMPLETED ·Phase: PHASE1

A Study to Evaluate GBT021601-012 Single Dose and Multiple Dose in Participants With Sickle Cell Disease (SCD)

NCT04983264 ·Status: COMPLETED ·Phase: PHASE1

Absorption, Metabolism, and Excretion of a Single Dose of Ferriprox® in Patients With Sickle Cell Disease

NCT01835496 ·Status: COMPLETED ·Phase: PHASE1

Pharmacokinetics, Pharmacodynamics and Safety of Epeleuton in Patients With Sickle Cell Disease

NCT05861453 ·Status: COMPLETED ·Phase: PHASE2

Dose Escalation Study of PF-07209326 in Healthy Participants and Participants With Sickle Cell Disease

NCT04255875 ·Status: COMPLETED ·Phase: PHASE1

An Assessment of Prasugrel on Healthy Adults and Sickle Cell Adults

NCT01178099 ·Status: COMPLETED ·Phase: PHASE1

A Research Study of the Effect of Food on Etavopivat in Healthy Participants

NCT06433661 ·Status: COMPLETED ·Phase: PHASE1

Defibrotide in Sickle Cell Disease-Related Acute Chest Syndrome

NCT03805581 ·Status: COMPLETED ·Phase: PHASE2

A Phase 2/3 Study in Adult and Adolescent Participants With SCD

NCT05431088 ·Status: RECRUITING ·Phase: PHASE2/PHASE3

Pharmacokinetics of Oral Hydroxyurea Solution

NCT03763656 ·Status: COMPLETED ·Phase: PHASE1/PHASE2

A Study to Evaluate Safety, Pharmacokinetic, and Biological Activity of INCB059872 in Subjects With Sickle Cell Disease

NCT03132324 ·Status: TERMINATED ·Phase: PHASE1

Safety, Tolerability and Pharmacokinetics of FTX-6058

NCT04586985 ·Status: COMPLETED ·Phase: PHASE1

A SAD/MAD to Assess the Safety, PK/PD of FT-4202 in Healthy Volunteers and Sickle Cell Disease Patients

NCT03815695 ·Status: COMPLETED ·Phase: PHASE1

A Study to Evaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients With Sickle Cell Disease

NCT06198712 ·Status: RECRUITING ·Phase: PHASE2

A Relative Bioavailability Study of a Prasugrel Orally Disintegrating Tablet

NCT01430091 ·Status: COMPLETED ·Phase: PHASE1

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects With Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of Mitapivat

NCT04610866 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

NCT06546670 ·Status: RECRUITING ·Phase: PHASE1/PHASE2

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Oral GSK4172239D Compared With Placebo in Sickle Cell Disease Participants Aged 18 to 50 Years

NCT05660265 ·Status: TERMINATED ·Phase: PHASE1

Optimizing Hydroxyurea Dosage With Pharmakokinetic in Patients Suffering of Moderate to Severe Sickle Cell Anemia

NCT06761560 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2/PHASE3

A Single Dose Study of the Safety, Blood Levels and Biological Effects of Aes-103 Compared to Placebo in Subjects With Stable Sickle Cell Disease

NCT01597401 ·Status: COMPLETED ·Phase: PHASE1

A Study of the Effect of IW-1701 (Olinciguat), a Stimulator of Soluble Guanylate Cyclase (sGC), on Patients With Sickle Cell Disease (SCD)

NCT03285178 ·Status: COMPLETED ·Phase: PHASE2

AB1 in Adult Patients with Sickle Cell Disease (SCD)

NCT05261711 ·Status: TERMINATED ·Phase: PHASE1/PHASE2

A Sickle CEll Disease ComplicatioN Trial

NCT02604368 ·Status: UNKNOWN ·Phase: PHASE3

A Dose-Finding Study of AG-348 in Sickle Cell Disease

NCT04000165 ·Status: COMPLETED ·Phase: EARLY_PHASE1

A Study to Test How Either a Capsule or a Tablet With NDec (Decitabine and Tetrahydrouridine) Works in the Body of Healthy People

NCT06291285 ·Status: COMPLETED ·Phase: PHASE1