Pharmacokinetics, Pharmacodynamics and Safety of Epeleuton in Patients With Sickle Cell Disease

AB1 in Adult Patients with Sickle Cell Disease (SCD)

NCT05261711 ·Status: TERMINATED ·Phase: PHASE1/PHASE2

A GBT021601 ADME Microtracer Study in Healthy Volunteers

NCT05718687 ·Status: COMPLETED ·Phase: PHASE1

N-Acetylcysteine in Patients With Sickle Cell Disease

NCT01849016 ·Status: COMPLETED ·Phase: PHASE3

Methadone in Pediatric and Adult Sickle Cell Patients

NCT00761085 ·Status: COMPLETED ·Phase: NA

A Relative Bioavailability Study of a Prasugrel Orally Disintegrating Tablet

NCT01430091 ·Status: COMPLETED ·Phase: PHASE1

Safety, Pharmacokinetic, and Pharmacodynamic Study of NKTT120 in Adult Patients With Stable Sickle Cell Disease (SCD)

NCT01783691 ·Status: COMPLETED ·Phase: PHASE1

A Dose-Finding Study of Tebapivat to Assess Efficacy, and Safety in Participants With Sickle Cell Disease (SCD)

NCT06924970 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2

Safety and Efficacy of Orally Administered NUV001 Nutraceutical Supplement in Sickle Cell Disease Patients

NCT05791591 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA

A Study to Evaluate Safety, Pharmacokinetic, and Biological Activity of INCB059872 in Subjects With Sickle Cell Disease

NCT03132324 ·Status: TERMINATED ·Phase: PHASE1

Study of the Effect of Etavopivat on Cerebral Hemodynamic Response in Children With Sickle Cell Disease

NCT05725902 ·Status: COMPLETED ·Phase: PHASE2

A Single-Dose Relative Bioavailability Study Of GBT440 300 mg Capsules in Healthy Subjects

NCT02567695 ·Status: COMPLETED ·Phase: PHASE1

A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease

NCT04055818 ·Status: RECRUITING ·Phase: PHASE1

Defibrotide in Sickle Cell Disease-Related Acute Chest Syndrome

NCT03805581 ·Status: COMPLETED ·Phase: PHASE2

Investigating the Mechanistic Effects of Mitapivat in Subjects With Sickle Cell Disease

NCT05675436 ·Status: ACTIVE_NOT_RECRUITING

GBT021601-022: A Study of GBT021601 in Participants With Sickle Cell Disease (SCD)

NCT05632354 ·Status: TERMINATED ·Phase: PHASE2/PHASE3

Trial of Zileuton CR in Children and Adults With Sickle Cell Disease

NCT01136941 ·Status: COMPLETED ·Phase: PHASE1

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

NCT06546670 ·Status: RECRUITING ·Phase: PHASE1/PHASE2

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-946 in Healthy Volunteers and in Participants With Sickle Cell Disease

NCT04536792 ·Status: COMPLETED ·Phase: PHASE1

Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease

NCT04819841 ·Status: RECRUITING ·Phase: PHASE1/PHASE2

Antioxidant Therapy to Reduce Inflammation in Sickle Cell Disease

NCT01054768 ·Status: COMPLETED ·Phase: PHASE2

A Study to Access the Safety/Efficacy of Thalidomide in the Treatment of Anemia in Patients With Myelodysplastic Syndromes

NCT00050843 ·Status: COMPLETED ·Phase: PHASE3

A Study to Evaluate GBT021601 in Single and Multiple Doses in Healthy Participants

NCT05036512 ·Status: COMPLETED ·Phase: PHASE1

Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507)

NCT03263559 ·Status: COMPLETED ·Phase: PHASE2

Prevention of Vaso-occlusive Painful Crisis by Using Omega-3 Fatty Acid Supplements

NCT02525107 ·Status: UNKNOWN ·Phase: PHASE3

An Assessment of Prasugrel on Healthy Adults and Sickle Cell Adults

NCT01178099 ·Status: COMPLETED ·Phase: PHASE1