Antegrade Autologous Blood Reinfusion After CPB
NCT07420582 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 130
Last updated 2026-02-24
Summary
This prospective observational study aims to evaluate the effect of antegrade pump blood reinfusion using the crystalloid "chase" technique on postoperative transfusion requirements in adult patients undergoing cardiac surgery with cardiopulmonary bypass. At the end of cardiopulmonary bypass, blood remaining within the cardiopulmonary bypass circuit is reinfused antegradely through the arterial line using a crystalloid chase, without collection or storage. Blood remaining within the bypass circuit after surgery represents a valuable source of autologous blood, and its reinfusion may contribute to perioperative blood conservation strategies. Patients receiving antegrade pump blood reinfusion via the chase technique will be compared with those managed without reinfusion, without any intervention by the investigators. The primary outcome is postoperative blood transfusion requirement.
Conditions
Interventions
- PROCEDURE
-
Antegrade Pump Blood Reinfusion
Adult patients undergoing cardiac surgery with cardiopulmonary bypass in whom antegrade pump blood reinfusion is performed at the end of bypass using the crystalloid chase technique, as part of routine clinical practice.
- OTHER
-
No Anterograde Pump Blood Reinfusion
Adult patients undergoing cardiac surgery with cardiopulmonary bypass in whom anterograde pump blood reinfusion is not performed at the end of bypass. Standard institutional clinical management is applied.
Sponsors & Collaborators
-
Kocaeli City Hospital
lead OTHER_GOV
Principal Investigators
-
Zeynep Yasemin Tavsanoglu, MD · Kocaeli City Hospital, Department of Anesthesiology and Reanimation
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-02-23
- Primary Completion
- 2026-06-01
- Completion
- 2026-06-15
Countries
- Turkey (Türkiye)
Study Locations
More Related Trials
-
Re-infusion of Unwashed Shed Blood During Off-pump Surgery
NCT06358079 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Acute Normovolemic Hemodilution in Off-pump CABG
NCT04042883 ·Status: UNKNOWN ·Phase: NA
-
Effect of Remote Ischemic Preconditioning on the Incidence of Acute Kidney Injury in Patients Undergoing Coronary Artery Bypass Graft Surgery
NCT02981680 ·Status: COMPLETED ·Phase: NA
-
The Sublingual Microcirculatory Alterations in Patients Undergoing Extracorporeal Flow Conditions
NCT02144298 ·Status: COMPLETED
-
Autonomic State, Cardiovascular Control and Outcomes in Coronary Surgery
NCT03169608 ·Status: UNKNOWN
-
Two Different Tranexamic Acid Regimens in Coronary Artery Bypass Surgery
NCT05994989 ·Status: COMPLETED
-
Biomarker and Thrombogenicity Assessment in Cardiopulmonary Bypass Surgery Utilizing Acute Normovolemic Hemodilution
NCT03326323 ·Status: COMPLETED
-
Miniaturized Extracorporeal Circulation Study
NCT03216720 ·Status: COMPLETED ·Phase: NA
-
CLEAR Trial: CA330 Cytokine Adsorption Column for Anticoagulant/Antiplatelet Patients in Non-Elective CPB Surgery.
NCT07284199 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Investigation of Myocardial Protection Level With Specific Cardioplegia Methods in Cardiac Surgery
NCT05603429 ·Status: COMPLETED
-
Cell Salvage and Retrograde Autologous Priming
NCT04792814 ·Status: COMPLETED
-
A Comparison of Etomidate and Ketamine for Anesthesia Induction in Coronary Artery Bypass Graft Surgery
NCT01386229 ·Status: UNKNOWN ·Phase: PHASE4
-
ICU Cell Saver to Reduce Blood Transfusions in Cardiac
NCT00950547 ·Status: COMPLETED ·Phase: NA
-
Antegrade and Retrograde Versurs Antegrade Cardioplegia in Complex Coronary Artery Bypass Surgeries
NCT04439162 ·Status: UNKNOWN ·Phase: NA
-
Use of Antithrombin in Cardiac Surgery With Cardiopulmonary Bypass
NCT00823082 ·Status: COMPLETED ·Phase: PHASE2
-
Protection During Cardiac Surgery.
NCT03230136 ·Status: COMPLETED ·Phase: NA
-
Comparison of Minimal Versus Conventional Extracorporeal Circulation in Coronary Surgery
NCT01603589 ·Status: COMPLETED ·Phase: NA
-
Fresh Autologous Whole Blood Transfusion After Cardiopulmonary Bypass
NCT03204357 ·Status: RECRUITING ·Phase: NA
-
Combination of Parasternal and Serratus Anterior Plane Block in Coronary Artery Bypass Graft Surgery
NCT06326333 ·Status: COMPLETED ·Phase: NA
-
Loop Isolation-based Uploading Pre-conditioning
NCT03766529 ·Status: UNKNOWN
-
Remote Ischemic Preconditioning in Type 2 Diabetic Patients Undergoing CABG
NCT06977230 ·Status: RECRUITING ·Phase: NA
-
Evaluation of Prophylactic Use of a Preoperative IABP in High-Risk Coronary Artery Bypass Graft Surgery
NCT03857906 ·Status: COMPLETED
-
Amino Acid Infusion in Cardiac Surgery
NCT07030933 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Myocardial Protection With Multiport Antegrade Cold Blood Cardioplegia
NCT02303704 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Cardiovascular Autonomic Neuropathy on AKI and Outcomes in Isolated CABG Surgery
NCT07254468 ·Status: COMPLETED