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Germline Genetic Testing of the TP53 Gene

NCT07419893 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1940

Last updated 2026-02-19

No results posted yet for this study

Summary

This is a retrospective, observational, single-center study designed as a cohort analysis. The study population will include consecutive patients referred for genetic counseling and TP53 germline genetic testing between 2004 and 2025 at the Division of Cancer Prevention and Genetics of the IEO. The primary endpoint is to determine the overall detection rate of Pathological Variants (PVs) in the TP53 gene among individuals referred to the institute and the differences between the groups.

Conditions

  • TP53 Gene Mutation
  • Multi-Gene Transcriptional Profiling
  • TP53 Gene Germline Mutation Carrier

Sponsors & Collaborators

  • European Institute of Oncology

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-01-29
Primary Completion
2026-07-31
Completion
2031-01-31

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07419893 on ClinicalTrials.gov