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" TREX1 Gene Mutations and Their Role in Systemic Lupus Erythematosus

NCT07397728 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2026-02-09

No results posted yet for this study

Summary

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease characterized by diverse clinical manifestations, prominently involving the skin.

Conditions

Interventions

DIAGNOSTIC_TEST

TREX1 gene polymorphisms

To assess the prevalence of selected autoantibodies as (anti-dsDNA, anti-Sm, anti-Ro/SSA, anti-La/SSB) and TREX1 gene polymorphisms in SLE patients, and their association with clinical features and disease activity

Sponsors & Collaborators

  • South Valley University

    lead OTHER

Principal Investigators

  • Eisa Mohammed Hegazy, Professor · Dermatology, Venereology and Andrology. Faculty of Medicine,Qena University

  • Mohammed Hosny Hassan, Professor · Biochemistry ,Qena faculty of medicine ,south valley university

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-06-10
Primary Completion
2026-06-01
Completion
2026-06-10

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07397728 on ClinicalTrials.gov